Vidal Nicole auteur aut IRD Bazepeo S. E. auteur aut IRD Mulanga C. auteur aut IRD Delaporte Eric auteur aut IRD Peeters Martine auteur aut IRD text journalArticle eng text/pdf born digital access In this study, we characterized HIV-1 strains from the Democratic Republic of Congo (DRC), previously described as divergent subtype A (n = 1,97CD.KMST91) or untypable (n = 7) in the V3-V5 env region. Four strains had the same structure over the entire genome, including alternating fragments of a new subsubtype, A5, within the subtype A radiation and fragments that remain unclassified. Therefore, the cluster of new viruses represents a new circulating recombinant, CRF26_A5U. Three additional strains were unique recombinants with the newly described CRF26_A5U and subtype C. Finally, the nearly full-length sequence of 97CD.KMST91 showed that this strain also consisted of alternating fragments of a divergent subtype A lineage and unclassified fragments, although different from previously reported A and U sequences. The high genetic distances among the different CRF26-A5U strains suggest their longstanding presence in the DRC. specialized 052 25 8 823-832 2009 0889-2229 https://www.documentation.ird.fr/hor/fdi:010048169 10.1089/aid.2008.0283 0889-2229 [F B010048169] https://www.documentation.ird.fr/hor/fdi:010048169 https://www.documentation.ird.fr/intranet/publi/2009/09/010048169.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2009-10-07 2017-08-23 fdi:010048169 fre