@article{fdi:010048169, title = {{G}enetic characterization of eight full-length {HIV} type 1 genomes from the democratic republic of {C}ongo ({DRC}) reveal a new subsubtype, {A}5, in the {A} radiation that predominates in the recombinant structure of {CRF}26_{A}5{U}}, author = {{V}idal, {N}icole and {B}azepeo, {S}. {E}. and {M}ulanga, {C}. and {D}elaporte, {E}ric and {P}eeters, {M}artine}, editor = {}, language = {{ENG}}, abstract = {{I}n this study, we characterized {HIV}-1 strains from the {D}emocratic {R}epublic of {C}ongo ({DRC}), previously described as divergent subtype {A} (n = 1,97{CD}.{KMST}91) or untypable (n = 7) in the {V}3-{V}5 env region. {F}our strains had the same structure over the entire genome, including alternating fragments of a new subsubtype, {A}5, within the subtype {A} radiation and fragments that remain unclassified. {T}herefore, the cluster of new viruses represents a new circulating recombinant, {CRF}26_{A}5{U}. {T}hree additional strains were unique recombinants with the newly described {CRF}26_{A}5{U} and subtype {C}. {F}inally, the nearly full-length sequence of 97{CD}.{KMST}91 showed that this strain also consisted of alternating fragments of a divergent subtype {A} lineage and unclassified fragments, although different from previously reported {A} and {U} sequences. {T}he high genetic distances among the different {CRF}26-{A}5{U} strains suggest their longstanding presence in the {DRC}.}, keywords = {}, booktitle = {}, journal = {{A}ids {R}esearch and {H}uman {R}etroviruses}, volume = {25}, numero = {8}, pages = {823--832}, ISSN = {0889-2229}, year = {2009}, DOI = {10.1089/aid.2008.0283}, URL = {https://www.documentation.ird.fr/hor/fdi:010048169}, }