@article{fdi:010046272, title = {{U}se of a histidine-rich protein 2-based rapid diagnostic test for malaria by health personnel during routine consultation of febrile outpatients in a peripheral health facility in {Y}aounde, {C}ameroon}, author = {{S}ayang, {C}. and {S}oula, {G}. and {T}ahar, {R}achida and {B}asco, {L}eonardo and {G}azin, {P}ierre and {M}oyou-{S}omo, {R}. and {D}elmont, {J}.}, editor = {}, language = {{ENG}}, abstract = {{T}he role of a rapid diagnostic test ({RDT}) in the case management of {P}lasmodium falciparum malaria infections has not been determined in {A}frica. {O}ur study was conducted during {N}ovember 2007-{J}anuary 2008 to assess test accuracy of an {RDT} in the management of febrile {O}utpatients {I}n a peripheral urban health facility ill found the overall sensitivity to be 71.4% and a specificity of 82.2%; the positive predictive {V}alue and negative predictive value were 73.8% and 80.4%, respectively. {F}alse-negative and false-positive cases represented 11.8% and 10.5% of all febrile patients. {M}alaria alone (31.3%) was the first {C}ause of fevers 33.5%, of fever {C}ases {W}ere of unknown origin. {A}cute respiratory infections were common among children 0-2 years of age (25.5%) and decreased with age. {T}he risk of having a {C}linical failure {W}ith the presumptive treatment of febrile children was seven times greater than that of the {RDT}-oriented management (relative risk = 6.8, 95% confidence interval = 0.88-53.4, {P} = 0.03) because of the delay of appropriate treatment of non-malarial febrile illness. {O}ur results {S}uggest that the {RDT} may be of limited utility for children greater than five years of age and adults and that diagnosis based oil microscopic examination of blood smears should be recommended for these patient populations, as {W}ell as in areas of low, transmission.}, keywords = {{YAOUNDE} ; {CAMEROUN}}, booktitle = {}, journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene}, volume = {81}, numero = {2}, pages = {343--347}, ISSN = {0002-9637}, year = {2009}, URL = {https://www.documentation.ird.fr/hor/fdi:010046272}, }