@article{fdi:010046204,
  title = {{T}rypanosoma cruzi : {N}ew insights on ecophylogeny and hybridization by multigene sequencing of three nuclear and one maxicircle genes},
  author = {{S}ubileau, {M}. and {B}arnab{\'e}, {C}hristian and {D}ouzery, {E}. {J}. {P}. and {D}iosque, {P}. and {T}ibayrenc, {M}ichel},
  editor = {},
  language = {{ENG}},
  abstract = {{N}atural populations of {T}rypanosoma cruzi are structured into five genetic lineages, {T} cruzi {I} and {T}. cruzi {II} a to e, as the result of clonal evolution with rare genetic recombination events. {T}o explore more in depth these phenomenons, a multigene sequencing approach was used, for the first time in the case of {T}. cruzi. {T}hree nuclear loci and a maxicircle locus were sequenced on 18 {T}. cruzi stocks. {S}equences were used to build phylogenetic trees from each locus and from concatenated sequences of all loci. {T}he data confirmed the hybrid origin of {DTU}s {II}d and {II}e, as the result of an ancient genetic recombination between strains pertaining to {II}b and {II}c. {T}he data confirmed also a hybrid origin of {DTU}s {II}a and {II}c. {C}ontrary to previous reports, we failed to detect mosaic genes. {T}he phylogenetic relationship between {DTU}s and the respective roles of recombination and selection were tested.},
  keywords = {{T}ryponosoma cruzi ; {K}inetoplastidae ; {M}ultigene sequencing ; {P}hylogeny ; {H}ybrid origins ; {R}ecombination ; {C}lonality ; {D}iscrete typing units},
  booktitle = {},
  journal = {{E}xperimental {P}arasitology},
  volume = {122},
  numero = {4},
  pages = {328--337},
  ISSN = {0014-4894},
  year = {2009},
  DOI = {10.1016/j.exppara.2009.04.008},
  URL = {https://www.documentation.ird.fr/hor/fdi:010046204},
}