%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Balraj, P.
%A Renesto, P.
%A Raoult, Didier
%T Advances in Rickettsia pathogenicity
%D 2009
%L fdi:010046181
%G ENG
%J Rickettsiology and Rickettsial Diseases
%@ 0077-8923
%K actin-based motility ; adhesins ; phagosomal escape ; PLD ; rickettsia ; T4SS
%M ISI:000267264400010
%P 94-105
%R 10.1111/j.1749-6632.2009.04517.x
%U https://www.documentation.ird.fr/hor/fdi:010046181
%> https://www.documentation.ird.fr/intranet/publi/2009/07/010046181.pdf
%V 1166
%W Horizon (IRD)
%X One century after the first description of rickettsiae as human pathogens, the rickettsiosis remained poorly understood diseases. These microorganisms are indeed characterized by a strictly intracellular location which has, for long, prohibited their detailed study. Within the last ten years, the completion of the genome sequences of several strains allowed gaining a better knowledge about the molecular mechanisms involved in rickettsia pathogenicity. Here, we summarized available data concerning the critical steps of rickettsia-host cell interactions that should contribute to tissue injury and diseases, that is, adhesion, phagosomal escape, motility, and intracellular survival of the bacteria.
%$ 052