@article{fdi:010046181, title = {{A}dvances in {R}ickettsia pathogenicity}, author = {{B}alraj, {P}. and {R}enesto, {P}. and {R}aoult, {D}idier}, editor = {}, language = {{ENG}}, abstract = {{O}ne century after the first description of rickettsiae as human pathogens, the rickettsiosis remained poorly understood diseases. {T}hese microorganisms are indeed characterized by a strictly intracellular location which has, for long, prohibited their detailed study. {W}ithin the last ten years, the completion of the genome sequences of several strains allowed gaining a better knowledge about the molecular mechanisms involved in rickettsia pathogenicity. {H}ere, we summarized available data concerning the critical steps of rickettsia-host cell interactions that should contribute to tissue injury and diseases, that is, adhesion, phagosomal escape, motility, and intracellular survival of the bacteria.}, keywords = {actin-based motility ; adhesins ; phagosomal escape ; {PLD} ; rickettsia ; {T}4{SS}}, booktitle = {}, journal = {{R}ickettsiology and {R}ickettsial {D}iseases}, volume = {1166}, numero = {}, pages = {94--105}, ISSN = {0077-8923}, year = {2009}, DOI = {10.1111/j.1749-6632.2009.04517.x}, URL = {https://www.documentation.ird.fr/hor/fdi:010046181}, }