@article{fdi:010046117, title = {{N}ew concepts for the old challenge of {A}frican relapsing fever borreliosis}, author = {{C}utler, {S}. {J}. and {A}bdissa, {A}. and {T}rape, {J}ean-{F}ran{\c{c}}ois}, editor = {}, language = {{ENG}}, abstract = {{R}elapsing fever, caused by spirochaetes belonging to the genus {B}orrelia, was once the cause of worldwide epidemic disease. {T}his was largely through infection with the louse-borne form of the disease, caused by {B}orrelia recurrentis (louse-borne relapsing fever ({LBRF})). {D}uring the last century, we have witnessed the demise of this infection, largely owing to improved standards of living and the introduction of the insecticide {DDT}, resulting in a reduction in the incidence of the body louse, the vector for relapsing fever. {I}n areas of extreme poverty this disease persists, causing a significant burden of disease. {I}t is now looking probable that this infection is caused by a louse-adapted variant of {B}orrelia duttonii, transmitted by {O}rnithodoros moubata'soft' ticks in {E}ast {A}frica. {L}ike {LBRF}, infection still causes impact, particularly affecting young children and pregnant women. {O}ver recent years, the true burden of relapsing fever caused by infection with the closely related {B}orrelia crocidurae, transmitted by {O}rnithodoros sonrai ticks, has only just begun to emerge. {H}ere, the current state of knowledge concerning relapsing fever in {A}frica is reviewed.}, keywords = {{B}orrelia ; louse-borne relapsing fever ; spirochaetes ; tick-borne relapsing fever}, booktitle = {}, journal = {{C}linical {M}icrobiology and {I}nfection}, volume = {15}, numero = {5}, pages = {400--406}, ISSN = {1198-743{X}}, year = {2009}, DOI = {10.1111/j.1469-0691.2009.02819.x}, URL = {https://www.documentation.ird.fr/hor/fdi:010046117}, }