Casalta J. P. auteur aut IRD Gouriet F. auteur aut IRD Roux V. auteur aut IRD Thuny F. auteur aut IRD Habib G. auteur aut IRD Raoult Didier auteur aut IRD text journalArticle eng text/pdf born digital access The SeptiFast test (Roche Diagnostics) is a new commercial molecular technique that has emerged for the detection of bacteria in blood. We compared in this study the sensitivity of blood culture to a commercially available broad-range real-time polymerase chain reaction (PCR) assay for the detection in blood of 19 bacterial species and six fungal species (SeptiFast test, Roche Diagnostics) in 63 patients with infectious endocarditis (IE). The SeptiFast test is not more sensitive for organisms such as Streptococci, Enterococci, and Staphylococcus aureus (11/29 versus 12/29 for blood culture). It has detected less commonly coagulase-negative Staphylococci (0/15 versus 3/15, P = 0.2) and significantly fewer other microorganisms (0/6 versus 4/6, P = 0.03). However, bacteria were detected from three IE treated by antibiotics, with blood culture negative on admission. The SeptiFast test may be useful in cases of IE in patients treated with antibiotics before admission. specialized 050 28 6 569-573 2009 0934-9723 https://www.documentation.ird.fr/hor/fdi:010046115 10.1007/s10096-008-0672-6 0934-9723 [F B010046115] https://www.documentation.ird.fr/hor/fdi:010046115 https://www.documentation.ird.fr/intranet/publi/2009/06/010046115.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2009-07-08 2017-08-23 fdi:010046115 fre