@article{fdi:010046097, title = {{T}he genetic structure and history of {A}fricans and {A}frican {A}mericans}, author = {{T}ishkoff, {S}.{A}. and {R}eed, {F}.{A}. and {F}riedlaender, {F}.{R}. and {E}hret, {C}. and {R}anciaro, {A}. and {F}roment, {A}lain and {H}irbo, {J}.{B}. and {A}womoyi, {A}.{A}. and {B}odo, {J}.{M}. and {D}oumbo, {O}. and {I}brahim, {M}. and {J}uma, {A}.{T}. and {K}otze, {M}.{J}. and {L}ema, {G}. and {M}oore, {J}.{H}. and {M}ortensen, {H}. and {N}yambo, {T}.{B}. and {O}mar, {S}.{A}. and {P}owell, {K}. and {P}retorius, {G}.{S}. and {S}mith, {M}.{W}. and {T}hera, {M}.{A}. and {W}ambebe, {C}. and {W}eber, {J}.{L}. and {W}illiams, {S}.{M}.}, editor = {}, language = {{ENG}}, abstract = {{A}frica is the source of all modern humans, but characterization of genetic variation and of relationships among populations across the continent has been enigmatic. {W}e studied 121 {A}frican populations, four {A}frican {A}merican populations, and 60 non-{A}frican populations for patterns of variation at 1327 nuclear microsatellite and insertion/deletion markers. {W}e identified 14 ancestral population clusters in {A}frica that correlate with self-described ethnicity and shared cultural and/or linguistic properties. {W}e observed high levels of mixed ancestry in most populations, reflecting historical migration events across the continent. {O}ur data also provide evidence for shared ancestry among geographically diverse hunter-gatherer populations ({K}hoesan speakers and {P}ygmies). {T}he ancestry of {A}frican {A}mericans is predominantly from {N}iger-{K}ordofanian (similar to 71%), {E}uropean (similar to 13%), and other {A}frican (similar to 8%) populations, although admixture levels varied considerably among individuals. {T}his study helps tease apart the complex evolutionary history of {A}fricans and {A}frican {A}mericans, aiding both anthropological and genetic epidemiologic studies.}, keywords = {{AFRIQUE} {SUBSAHARIENNE} ; {AMERIQUE} {DU} {NORD}}, booktitle = {}, journal = {{S}cience}, volume = {324}, numero = {5930}, pages = {1035--1044}, ISSN = {0036-8075}, year = {2009}, DOI = {10.1126/science.1172257}, URL = {https://www.documentation.ird.fr/hor/fdi:010046097}, }