@article{fdi:010046058,
  title = {{P}yrethrum : a mixture of natural pyrethrins has potential for malaria vector control},
  author = {{D}uchon, {S}t{\'e}phane and {B}onnet, {J}ulien and {M}arcombe, {S}{\'e}bastien and {Z}aim, {M}. and {C}orbel, {V}incent},
  editor = {},
  language = {{ENG}},
  abstract = {{P}yrethrum is a natural mixture of six insecticidal esters, recognized for low mammalian toxicity and limited persistence in the environment. {I}n this study, {W}orld {H}ealth {O}rganization standard bioassays were {U}sed to evaluate the performance of pyrethrum against both susceptible and pyrethroid-resistant {A}nopheles gambiae s.s. vie results showed that the intrinsic activity of pyrethrum was similar to that of permethrin but lower than that of deltamethrin against susceptible mosquitoes, {H}owever, pyrethrum was less affected by the presence of the kdr mutation than synthetic pyrethroids (with lower resistance ratios) and showed good knock-down effect, repellency, and blood-feeding inhibition against the pyrethroid-resistant strain. {I}n laboratory condition, mosquito nets treated with 500-1,000 mg/m(2) (pyrethrum) remained effective, i.e., >80% mortality and/or >95% {K}-{D} effect, for 9 mo. {C}onversely, the efficacy and residual activity of pyrethrum ({P}ynet 5% {EC}) on substrates {W}as not conclusive, especially concerning {M}od, which is it porous subtrate (mortality <80% after 3 mo at 2g/m(2)) {T}hese finding suggested that pyrethrum may be a potential alternative candidate {F}or the impregnation of mosquito nets and textiles in are-as where resistance to pyrethroids has become problematic.},
  keywords = {{A}nopheles gambiae ; pyrethrum ; inseticide-treated nets ; indoor residual spraying ; pyrethroid resistance},
  booktitle = {},
  journal = {{J}ournal of {M}edical {E}ntomology},
  volume = {46},
  numero = {3},
  pages = {516--522},
  ISSN = {0022-2585},
  year = {2009},
  URL = {https://www.documentation.ird.fr/hor/fdi:010046058},
}