@article{fdi:010046046,
  title = {{A}ndes virus antigens are shed in urine of patients with acute hantavirus cardiopulmonary syndrome},
  author = {{G}odoy, {P}. and {M}arsac, {D}. and {S}tefas, {E}. and {F}errer, {P}. and {T}ischler, {N}. {D}. and {P}ino, {K}. and {R}amdohr, {P}. and {V}ial, {P}. and {V}alenzuela, {P}. {D}. {T}. and {F}erres, {M}. and {V}eas, {F}rancisco and {L}opez-{L}astra, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{H}antavirus cardiopulmonary syndrome ({HCPS}) is a highly pathogenic emerging disease (40% case fatality rate) caused by {N}ew {W}orld hantaviruses. {H}antavirus infections are transmitted to humans mainly by inhalation of virus-contaminated aerosol particles of rodent excreta and secretions. {A}t present, there are no antiviral drugs or immunotherapeutic agents available for the treatment of hantaviral infection, and the survival rates for infected patients hinge largely on early virus recognition and hospital admission and aggressive pulmonary and hemodynamic support. {I}n this study, we show that {A}ndes virus ({ANDV}) interacts with human apolipoprotein {H} ({A}po{H}) and that {A}po{H}-coated magnetic beads or {A}po{H}-coated enzyme-linked immunosorbent assay plates can be used to capture and concentrate the virus from complex biological mixtures, such as serum and urine, allowing it to be detected by both immunological and molecular approaches. {I}n addition, we report that {ANDV}-antigens and infectious virus are shed in urine of {HCPS} patients.},
  keywords = {},
  booktitle = {},
  journal = {{J}ournal of {V}irology},
  volume = {83},
  numero = {10},
  pages = {5046--5055},
  ISSN = {0022-538{X}},
  year = {2009},
  DOI = {10.1128/jvi.02409-08},
  URL = {https://www.documentation.ird.fr/hor/fdi:010046046},
}