@article{fdi:010046020, title = {{T}rypanosoma cruzi : adaptation to its vectors and its hosts}, author = {{N}oireau, {F}ran{\c{c}}ois and {D}iosque, {P}. and {J}ansen, {A}. {M}.}, editor = {}, language = {{ENG}}, abstract = {{A}merican trypanosomiasis is a parasitic zoonosis that occurs throughout {L}atin {A}merica. {T}he etiological agent, {T}rypanosoma cruzi, is able to infect almost all tissues of its mammalian hosts and spreads in the environment in multifarious transmission cycles that may or not be connected. {T}his biological plasticity, which is probably the result of the considerable heterogeneity of the taxon, exemplifies a successful adaptation of a parasite resulting in distinct outcomes of infection and a complex epidemiological pattern. {I}n the 1990s, most endemic countries strengthened national control programs to interrupt the transmission of this parasite to humans. {H}owever, many obstacles remain to the effective control of the disease. {C}urrent knowledge of the different components involved in elaborate system that is {A}merican trypanosomiasis (the protozoan parasite {T}. cruzi, vectors {T}riatominae and the many reservoirs of infection), as well as the interactions existing within the system, is still incomplete. {T}he {T}riatominae probably evolve from predatory reduvids in response to the availability of vertebrate food source. {H}owever, the basic mechanisms of adaptation of some of them to artificial ecotopes remain poorly understood. {N}evertheless, these adaptations seem to be associated with a behavioral plasticity, a reduction in the genetic repertoire and increasing developmental instability.}, keywords = {{T}rypanosoma cruzi ; {T}riatominae ; mammalian host ; vectorial transmission ; adaptative strategies}, booktitle = {}, journal = {{V}eterinary {R}esearch}, volume = {40}, numero = {}, pages = {26}, ISSN = {0928-4249}, year = {2009}, DOI = {10.1051/vetres/2009009}, URL = {https://www.documentation.ird.fr/hor/fdi:010046020}, }