@article{fdi:010046004,
  title = {{I}nnovative applications for insect viruses : towards insecticide sensitization},
  author = {{L}apied, {B}. and {P}ennetier, {C}{\'e}dric and {A}paire {M}archais, {V}. and {L}icznar, {P}. and {C}orbel, {V}incent},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he effective management of emerging insect-borne disease is dependent on the use of safe and efficacious chemical insecticides. {G}iven the inherent ability of insects to develop resistance, it is essential to propose innovative strategies because insecticides remain the most important element of integrated approaches to vector control. {R}ecently, intracellular phosphorylation and dephosphorylation of membrane receptors and ion channels targeted by insecticides have been described as new processes for increasing the sensitivity of insecticides. {A}n efficient method might be to infect host insects with recombinant viruses overexpressing specific protein phosphatases/kinases known to regulate specific insecticide-sensitive targets. {T}his attractive strategy could lead to sensitization of the insects, thus reducing the doses of insecticides and increasing the efficacy of treatments.},
  keywords = {},
  booktitle = {},
  journal = {{T}rends in {B}iotechnology},
  volume = {27},
  numero = {4},
  pages = {190--198},
  ISSN = {0167-7799},
  year = {2009},
  DOI = {10.1016/j.tibtech.2008.12.005},
  URL = {https://www.documentation.ird.fr/hor/fdi:010046004},
}