@article{fdi:010044975,
  title = {{G}enome sequence and rapid evolution of the rice pathogen {X}anthomonas oryzae pv. oryzae {PXO}99{A}},
  author = {{S}alzberg, {S}.{L}. and {S}ommer, {D}.{D}. and {S}chatz, {M}.{C}. and {P}hillippy, {A}.{M}. and {R}abinowicz, {P}.{D}. and {T}suge, {S}. and {F}urutani, {A}. and {O}chiai, {H}. and {D}elcher, {A}.{L}. and {K}elley, {D}. and {M}adupu, {R}. and {P}uiu, {D}. and {R}adune, {D}. and {S}humway, {M}. and {T}rapnell, {C}. and {A}parna, {G}. and {J}ha, {G}. and {P}andey, {A}. and {P}atil, {P}.{B}. and {I}shihara, {H}. and {M}eyer, {D}.{F}. and {S}zurek, {B}oris and {V}erdier, {V}al{\'e}rie and {K}oebnik, {R}alf and {D}ow, {J}.{M}. and {R}yan, {R}.{P}. and {H}irata, {H}. and {T}suyumu, {S}. and {S}ang {W}on {L}ee and {R}onald, {P}.{C}. and {S}onti, {R}.{V}. and {V}an {S}luys, {M}.{A}. and {L}each, {J}.{E}. and {W}hite, {F}.{F}. and {B}ogdanove, {A}.{J}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {X}anthomonas  oryzae  pv.  oryzae  causes  bacterial  blight  of  rice  ({O}ryza  sativa  {L}.),  a major disease that constrains production of this staple crop in many parts of the world. {W}e report here on the complete genome sequence of strain {PXO}99{A} and its comparison to two previously sequenced strains, {KACC}10331 and {MAFF}311018, which are highly similar to one another. {R}esults: {T}he  {PXO}99{A} genome  is  a  single  circular  chromosome  of  5,240,075  bp,  considerably longer than the genomes of the other strains (4,941,439 bp and 4,940,217 bp, respectively), and it contains  5083  protein-coding  genes,  including  87  not  found  in  {KACC}10331  or  {MAFF}311018. {PXO}99{A} contains a greater  number  of  virulence-associated  transcription  activator-like  effector genes  and  has  at  least  ten  major  chromosomal  rearrangements  relative  to  {KACC}10331  and{MAFF}311018.  {PXO}99{A} contains  numerous  copies  of  diverse  insertion  sequence  elements, members of which are associated with 7 out of 10 of the major rearrangements. {A} rapidly-evolving {CRISPR} (clustered regularly interspersed short palindromic repeats) region contains evidence of dozens of phage infections unique to the {PXO}99{A} lineage. {PXO}99{A} also contains a unique, near-perfect tandem repeat of 212 kilobases close to the replication terminus. {C}onclusion: {O}ur results provide striking evidence of genome plasticity and rapid evolution within {X}anthomonas  oryzae  pv.  oryzae.  {T}he  comparisons  point  to  sources  of  genomic  variation  and candidates for strain-specific adaptations of this pathogen that help to explain the extraordinary diversity  of  {X}anthomonas  oryzae  pv.  oryzae  genotypes  and  races  that  have  been  isolated  from around the world.},
  keywords = {{PATHOLOGIE} {VEGETALE} ; {RIZ} ; {AGENT} {PATHOGENE} ; {GENOTYPE} ; {VARIABILITE} {GENETIQUE} ; {PHYLOGENIE} ; {EVOLUTION} ; {RELATION} {HOTE} {PARASITE} ; {ETUDE} {EXPERIMENTALE} ; {ETUDE} {COMPARATIVE} ; {GENOME} ; {ANALYSE} {GENETIQUE} ; {TECHNIQUE} {PCR}},
  booktitle = {},
  journal = {{B}io{M}ed {C}entral {G}enomics},
  volume = {9},
  numero = {204},
  pages = {1--16},
  ISSN = {1471-2164},
  year = {2008},
  DOI = {10.1186/1471-2164-9-204},
  URL = {https://www.documentation.ird.fr/hor/fdi:010044975},
}