@article{fdi:010044358,
  title = {{C}omparative proteomic study of the venom of the piscivorous cone snail {C}onus consors},
  author = {{B}iass, {D}. and {D}utertre, {S}. and {G}erbault, {A}. and {M}enou, {J}ean-{L}ouis and {O}fford, {R}. and {F}avreau, {P}. and {S}tocklin, {R}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}n the context of an exhaustive study of the piscivorous cone snail {C}onus consors, we performed an in-depth analysis of the intact molecular masses that can be detected in the animal's venom, using {MALDI} and {ESI} mass spectrometry. {W}e clearly demonstrated that, for the venom of this species at least, it is essential to use both techniques in order to obtain the broadest data set of molecular masses. {O}nly 20% of the total number of molecules detected were found in both mass lists. {T}he two data sets were also compared in terms of mass range and relative hydrophobicity of the components detected in each. {W}ith a view to an extensive analysis of this venom's proteome, we further performed a comparative study by {ESI}-{MS} between venom obtained after classical dissection of the venom duct versus venom obtained by milking live animals. {S}urprisingly, although many fewer components were found in the milked venom than in the dissected venom, similar to 50% of those found had not been seen in the dissected venom. {S}everal questions raised by these observations are discussed. {W}ith regards to the current knowledge of the cone snail venom composition, our results emphasize the complementary nature of the mass spectrometry methods and of the two techniques used in venom collection.},
  keywords = {{C}one snail ; {C}onopeptide ; {C}onotoxin ; {C}onus consors ; {ESI}-{MS} ; {HPLC} ; {H}ydrophobicity ; {MALDI}-{TOF}-{MS} ; {M}ass fingerprint ; {M}ass range ; {M}ass spectrometry ; {P}eptide ; {P}eptidomics ; {P}roteomics ; {T}oxins ; {V}enom ; {V}enomics},
  booktitle = {},
  journal = {{J}ournal of {P}roteomics},
  volume = {72},
  numero = {2},
  pages = {210--218},
  ISSN = {1874-3919},
  year = {2009},
  DOI = {10.1016/j.jprot.2009.01.019},
  URL = {https://www.documentation.ird.fr/hor/fdi:010044358},
}