@article{fdi:010044342,
  title = {{F}our anti-protozoal and anti-bacterial compounds from {T}apirira guianensis},
  author = {{R}oumy, {V}. and {F}abre, {N}. and {P}ortet, {B}. and {B}ourdy, {G}enevi{\`e}ve and {A}cebey, {L}. and {V}igor, {C}. and {V}alentin, {A}. and {M}oulis, {C}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}apirira guianensis is a common tree used in traditional medicine in {F}rench {G}uiana against several infectious diseases (malaria, leishmaniasis, bacteria, etc.). {T}he bioassay-guided purification of {CH}2{C}l2 bark extract led to the isolation of four cyclic alkyl polyol derivatives: 4,6,2'-trihydroxy-6-[10'({Z})-heptadecenyl]-1-cyclohexen-2-one (1a), 1,4,6-trihydroxy-1,2'-epoxy-6-[10'({Z})-heptadecenyl]-2-cyclohexene (1b), 1,4,5,2'-tetrahydroxy-1-[10'({Z})-heptadecenyl]-2-cyclohexene (2), and 1,3,4,6-tetrahydroxy-1,2'-epoxy-6-[10'({Z})-heptadecenyl]-cyclohexane (3). {T}he structures were established on the basis of {ID} and 2{D} {NMR} analyses. {T}he anti-leishmanial, anti-plasmodial, anti-bacterial (on {S}taphylococcus aureus, {S}taphylococcus epidermidis and {E}scherichia coli), and anti-fungal (on {C}andida albicans) activities of the extracts and of these original compounds were evaluated. {T}wo showed medicinal interest supporting the traditional uses of the plant. {T}he structures were established through spectral analyses of the isolates and their derivatives.},
  keywords = {{T}apirira guianensis {A}ubl ; {A}nacardiaceae ; {C}yclic alkyl polyol ; derivatives ; {A}nti-plasmodial ; {A}nti-leishmanial ; {A}nti-bacterial ; {P}lasmodium falciparum ; {L}eishmania amazonensis},
  booktitle = {},
  journal = {{P}hytochemistry},
  volume = {70},
  numero = {2},
  pages = {305--311},
  ISSN = {0031-9422},
  year = {2009},
  DOI = {10.1016/j.phytochem.2008.10.003},
  URL = {https://www.documentation.ird.fr/hor/fdi:010044342},
}