@article{fdi:010044288,
  title = {{I}dentification of protein candidates for the serodiagnosis of {Q} fever endocarditis by an immunoproteomic approach},
  author = {{S}ekeyova, {Z}. and {K}owalczewska, {M}. and {D}ecloquement, {P}. and {P}elletier, {N}. and {S}pitalska, {E}. and {R}aoult, {D}idier},
  editor = {},
  language = {{ENG}},
  abstract = {{Q} fever is a worldwide zoonosis caused by {C}oxiella burnetii bacterium. {T}wo clinical forms are present: acute {Q} fever and chronic disease, including endocarditis. {C}urrently, the diagnosis of {Q} fever endocarditis is based on the detection of anti-phase {I} antibodies. {T}he objective of the study was to identify candidate proteins for the serological diagnosis of endocarditis due to {C}. burnetii. {T}he immunoreactivities of sera from 12 patients with {C}. burnetii infections, including the sera from patients with endocarditis and with the acute clinical form of {Q} fever, were compared with those of three control subjects who did not have {Q} fever. {W}e identified 29 candidate antigenic proteins by mass spectrometry. {T}wo proteins, arginine repressor and {O}mp{H}, were recognised exclusively by the sera of patients with {Q} fever endocarditis. {T}hese proteins are promising candidates for the development of serodiagnostic assays for {Q} fever endocarditis.},
  keywords = {},
  booktitle = {},
  journal = {{E}uropean {J}ournal of {C}linical {M}icrobiology and {I}nfectious {D}iseases},
  volume = {28},
  numero = {3},
  pages = {287--295},
  ISSN = {0934-9723},
  year = {2009},
  DOI = {10.1007/s10096-008-0621-4},
  URL = {https://www.documentation.ird.fr/hor/fdi:010044288},
}