Odilon Kikouama J. R. auteur aut IRD Le Cornec Florence auteur aut IRD Bouttier S. auteur aut IRD Launay A. auteur aut IRD Baldé L. auteur aut IRD Yagoubi N. auteur aut IRD text journalArticle eng text/pdf born digital access Physicochemical simulation (pH, electrolytes and temperature) of three physiological media was carried out in order to follow the release of trace elements contained in seven edible clays (mainly kaolinite, illite, muscovite and quartz) collected from the West African countries of Cote d'Ivoire, Guinee and Senegal. These clays are ingested by pregnant women for diverse reasons that are related to their condition. Simulated oral (6.5pH7), stomach (pH approximately 1.8) and intestinal (pH approximately 8.3) media were prepared separately in order to compare the quantities of the trace elements released. Samples were analyzed by inductively coupled plasma emission spectrometry and spectrophotometry for the evaluation of copper, iron ((Fe(II) and Fe(III)), lead, manganese, nickel and zinc, since some of these elements can palliate deficiency problems and others can induce toxic effects. The quantities of the chemical elements released were pH dependent. The lower the pH, the higher the quantities of copper, Fe(III) and zinc. The quantities of Fe(II) were similar at both lower (stomach) and higher (intestinal) pH values. However, the quantities of manganese, nickel and lead were lower than quantification limits. Heating (110C) of the clays increased the quantities of trace elements released and could also participate in the microbiological 'decontamination' of raw materials. Microbiological analysis shows that all samples tested were in compliance with the recommendations of the European Pharmacopoeia. To verify the existence of possible beneficial and hazardous effects on human health, the quantities of copper, iron and zinc were compared with the recommended allowances for trace elements in France. In addition, the quantities of manganese, nickel and lead were compared with the maximum admissible concentrations in drinking water. specialized Edible clays trace elements kinetic release physicochemically simulated physiological media microbiological quality 054 020 60 2 130-142 2009 0963-7486 https://www.documentation.ird.fr/hor/fdi:010044279 10.1080/09637480701614956 0963-7486 [F B010044279] https://www.documentation.ird.fr/hor/fdi:010044279 https://www.documentation.ird.fr/intranet/publi/depot/2020-06-26/010044279.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2009-03-06 2020-07-02 fdi:010044279 fre