@article{fdi:010044265, title = {{I}nfluence of wasting and stunting at the onset of the rainy season on subsequent malaria morbidity among rural preschool children in {S}enegal}, author = {{F}illol, {F}lorie and {C}ournil, {A}mandine and {B}oulanger, {D}enis and {C}iss{\'e}, {B}. and {S}okhna, {C}heikh and {T}argett, {G}. and {T}rape, {J}ean-{F}ran{\c{c}}ois and {S}imondon, {F}ran{\c{c}}ois and {G}reenwood, {B}. and {B}ork {S}imondon, {K}irsten}, editor = {}, language = {{ENG}}, abstract = {{I}n sub-{S}aharan {A}frica, malaria and malnutrition are major causes of morbidity and mortality in children less than five years of age. {T}o explore the impact of malnutrition on subsequent susceptibility to malaria, a cohort of 874 rural preschool children in {S}enegal was followed-up during one malaria transmission season from {J}uly through {D}ecember. {D}ata on nutritional status and {P}lasmodium falciparum parasitemia were collected at baseline. {M}alaria morbidity was monitored through weekly home visits. {W}asted children (weight-for-height z-score < -2) were at lower risk of having at least one subsequent clinical malaria attack (odds ratio = 0.33; 95% confidence interval = 0.13-0.81, {P} = 0.02), whereas stunting (height-for-age z-score < -2) or being underweight (weight-for-age z-score < -2) was not associated with clinical malaria. {A}lthough non-biological explanations such as overprotection of wasted children by their mothers should be considered, immunomodulation according to nutritional status could explain the lower risk of malaria attack among wasted children.}, keywords = {}, booktitle = {}, journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene}, volume = {80}, numero = {2}, pages = {202--208}, ISSN = {0002-9637}, year = {2009}, URL = {https://www.documentation.ird.fr/hor/fdi:010044265}, }