@article{fdi:010044244, title = {{E}xploring the origin and degree of genetic isolation of {A}nopheles gambiae from the islands of {S}ao {T}ome and {P}rincipe, potential sites for testing transgenic-based vector control}, author = {{M}arshall, {J}. {C}. and {P}into, {J}. and {C}harlwood, {J}. {D}. and {G}entile, {G}. and {S}antolamazza, {F}. and {S}imard, {F}r{\'e}d{\'e}ric and della {T}orre, {A}. and {D}onnelly, {M}. {J}. and {C}accone, {A}.}, editor = {}, language = {{ENG}}, abstract = {{T}he evolutionary processes at play between island and mainland populations of the malaria mosquito vector {A}nopheles gambiae sensu stricto are of great interest as islands may be suitable sites for preliminary application of transgenic-based vector control strategies. {S}ao {T}ome and {P}rincipe, located off the {W}est {A}frican coast, have received such attention in recent years. {T}his study investigates the degree of isolation of {A}n. gambiae s.s. populations between these islands and the mainland based on mitochondrial and ribosomal {DNA} molecular data. {W}e identify possible continental localities from which these island populations derived. {F}or these purposes, we used {F}-{ST} values, haplotype networks, and nested clade analysis to estimate migration rates and patterns. {H}aplotypes from both markers are geographically widespread across the {A}frican continent. {R}esults indicate that the populations from {S}ao {T}ome and {P}rincipe are relatively isolated from continental {A}frican populations, suggesting they are promising sites for test releases of transgenic individuals. {T}hese island populations are possibly derived from two separate continental migrations. {T}his result is discussed in the context of the history of the {A}frican slave trade with respect to {S}ao {T}ome and {P}rincipe.}, keywords = {{A}nopheles gambiae ; island colonization ; malaria ; mitochondrial {DNA} ; phylogeography ; ribosomal {DNA}}, booktitle = {}, journal = {{E}volutionary {A}pplications}, volume = {1}, numero = {4}, pages = {631--644}, ISSN = {1752-4571}, year = {2008}, DOI = {10.1111/j.1752-4571.2008.00048.x}, URL = {https://www.documentation.ird.fr/hor/fdi:010044244}, }