@article{fdi:010044239,
  title = {{S}tudy of bovine trypanotolerance by whole transcriptome analysis : toward identification of the involved genes},
  author = {{B}erthier, {D}. and {C}hantal, {I}. and {T}hevenon, {S}. and {S}akande, {H}. and {M}aillard, {J}. {C}. and {B}engaly, {Z}. and {P}iquemal, {D}. and {M}arti, {J}. and {C}uny, {G}{\'e}rard},
  editor = {},
  language = {{ENG}},
  abstract = {{A}frican trypanosomiases are parasitic diseases transmitted by tse-tse flies, considered as the main sanitary obstacle to animal production development in sub-{S}aharan {A}frica. {H}owever, if trypanosomiases have dramatic consequences on zebu ({B}os indicus) populations, they have a weaker impact on the western {A}frican taurine ({B}os taurus), which is known to be naturally tolerant to trypanosome infection. {M}echanisms governing this trypanotolerant trait are still poorly understood, but today, recent postgenomic biotechnologies, such as the {SAGE} technique (serial analysis of gene expression) allow us to explore the full transcriptome. {T}welve {SAGE} libraries were constructed from two trypanotolerant animals ({N}'{D}ama and {B}aoule) and one susceptible species of cattle (the {S}udanese zebu) during an experimental {T}rypanosoma congolense infection; 43,458 different tags were obtained at several particular points during the infection (before infection, at the maximum of parasitemia, the maximum of anemia, and at the end of the experiment after value normalization). {B}ioinformaties analyses highlighted some interesting gene variations with respect to the trypanotolerance status of the animal.},
  keywords = {{SAGE} ; trypanotolerance ; {T}rypanosoma congolense ; cattle},
  booktitle = {},
  journal = {{A}nnals of the {N}ew {Y}ork {A}cademy of {S}ciences},
  volume = {1149},
  numero = {},
  pages = {71--76},
  ISSN = {0077-8923},
  year = {2008},
  DOI = {10.1196/annals.1428.062},
  URL = {https://www.documentation.ird.fr/hor/fdi:010044239},
}