@article{fdi:010044238,
  title = {"{P}athogeno-{P}roteomics" toward a new approach of host-vector-pathogen interactions},
  author = {{H}olzmuller, {P}hilippe and {G}r{\'e}baut, {P}ascal and {B}rizard, {J}ean-{P}aul and {B}erthier, {D}. and {C}hantal, {I}. and {B}ossard, {G}. and {B}ucheton, {B}runo and {V}ezilier, {F}. and {C}huchana, {P}. and {B}ras {G}oncalves, {R}achel and {L}emesre, {J}ean-{L}oup and {V}incendeau, {P}. and {C}uny, {G}{\'e}rard and {F}rutos, {R}. and {B}iron, {D}. {G}.},
  editor = {},
  language = {{ENG}},
  abstract = {{M}any scientists working on pathogens (viruses, bacteria, fungi, parasites) are betting heavily on data generated by longitudinal genomic-transcriptomic-proteomic studies to explain biochemical host-vector-pathogen interactions and thus to contribute to disease control. {A}vailability of genome sequences of various organisms, from viruses to complex metazoans, led to the discovery of the functions of the genes themselves. {T}he postgenomic era stimulated the development of proteomic and bioinformatics tools to identify the locations, functions, and interactions of the gene products in tissues and/or cells of living organisms. {B}ecause of the diversity of available methods and the level of integration they promote, proteomics tools are potentially able to resolve interesting issues specific not only to host-vector-pathogen interactions in cell immunobiology, but also to ecology and evolution, population biology, and adaptive processes. {T}hese new analytical tools, as all new tools, contain pitfalls directly related to experimental design, statistical treatment, and protein identification. {N}evertheless, they offer the potency of building large protein-protein interaction networks for in silica, analysis of novel biological entities named "interactomes," a way of modeling host-vector-pathogen interactions to define new interference strategies.},
  keywords = {host-vector-pathogen interactions ; proteomics ; interactome ; modeling},
  booktitle = {},
  journal = {{A}nnals of the {N}ew {Y}ork {A}cademy of {S}ciences},
  volume = {1149},
  numero = {},
  pages = {66--70},
  ISSN = {0077-8923},
  year = {2008},
  DOI = {10.1196/annals.1428.061},
  URL = {https://www.documentation.ird.fr/hor/fdi:010044238},
}