@article{fdi:010044150, title = {{I}ntermittent preventive antimalarial treatment to children ({IPT}c) : firebreak or fire trap ?}, author = {{B}uffet, {P}. {A}. and {B}riand, {V}al{\'e}rie and {R}enia, {L}. and {T}hellier, {M}. and {D}anis, {M}. and {M}azier, {D}.}, editor = {}, language = {{ENG}}, abstract = {{I}ntermittent preventive treatment is the prescheduled administration of antimalarial drugs to at-risk patients in endemic areas. {T}his approach, which is recommended for pregnant women, is being evaluated in children. {S}ulfadoxine-pyrimethamine plus amodiaquine recently proved to be more protective than artemisinin-containing regimens. {T}herefore, the use of artemisinin derivatives could potentially be restricted to symptomatic patients. {D}eterminants of three pending issues: safety, efficacy throughout childhood, and effectiveness - the latter depending on the implementation of sustainable delivery mechanisms - are analyzed in this comment.}, keywords = {}, booktitle = {}, journal = {{T}rends in {P}arasitology}, volume = {24}, numero = {11}, pages = {482--485}, ISSN = {1471-4922}, year = {2008}, DOI = {10.1016/j.pt.2008.07.007}, URL = {https://www.documentation.ird.fr/hor/fdi:010044150}, }