@article{fdi:010044140,
  title = {{T}yrosol degradation via the homogentisic acid pathway in a newly isolated {H}alomonas strain from olive processing effluents},
  author = {{L}iebgott, {P}ierre-{P}ol and {L}abat, {M}arc and {A}mouric, {A}gn{\`e}s and {T}holozan, {J}ean-{L}uc and {L}orquin, {J}ean},
  editor = {},
  language = {{ENG}},
  abstract = {{T}o isolate a new {H}alomonas sp. strain capable of degrading tyrosol, a toxic compound present in olive mill wastewater, through the homogentisic acid ({HGA}) pathway. {A} moderately halophilic {G}ram-negative bacterium belonging to the {H}alomonas genus and designated strain {TYRC}17 was isolated from olive processing effluents. {T}his strain was able to completely degrade tyrosol (2-(p-hydroxyphenyl)-ethanol), a toxic compound found in such effluent. {T}yrosol degradation begins by an oxidation to 4-hydroxyphenylacetic acid ({HPA}), which is then converted into {HGA} by an {HPA} 1-monooxygenase, while closest {H}alomonas species degrade tyrosol through 3,4-dihydroxyphenylacetic acid ({DHPA}). {I}n the presence of transition metals, {HGA} underwent a p{H}-dependent abiotic conversion into benzoquinone acetic acid, then into 2,5-dihydroxybenzaldehyde (gentisaldehyde) and pyomelanin, by oxidative decarboxylation and polymerization, respectively. {T}yrosol degradation via {HGA} by the new {H}alomonas sp. strain {TYRC}17 was complete in the absence of trace elements. {I}n their presence, {HGA} was abiotically converted into gentisaldehyde and pyomelanin. {T}his is the first report on tyrosol degradation via the {HGA} pathway under hypersaline conditions and on the oxidative decarboxylation of {HGA} into gentisaldehyde. {I}t underlines the importance of the {H}alomonas genus in the bioremediation of toxic-contaminated sites.},
  keywords = {{G}entisaldehyde ; {H}alomonas ; homogentisic acid ; pyomelanin ; tyrosol},
  booktitle = {},
  journal = {{J}ournal of {A}pplied {M}icrobiology},
  volume = {105},
  numero = {6},
  pages = {2084--2095},
  ISSN = {1364-5072},
  year = {2008},
  DOI = {10.1111/j.1365-2672.2008.03925.x},
  URL = {https://www.documentation.ird.fr/hor/fdi:010044140},
}