@article{fdi:010043757, title = {{C}ase report : {E}ncephalopathy after ivermectin treatment in a patient infected with {L}oa loa and {P}lasmodium spp}, author = {{K}amgno, {J}. and {B}oussinesq, {M}ichel and {L}abrousse, {F}. and {N}kegoum, {B}. and {T}hylefors, {B}. {I}. and {M}ackenzie, {C}. {D}.}, editor = {}, language = {{ENG}}, abstract = {{D}espite over 350 million people being safely treated with ivermectin, there have been rare cases of death post-treatment; these events are most often associated with high {L}oa loa microfilaremia. {T}his first autopsy description of an encephalopathy case following the administration of ivermectin involves a 45-year-old male who became comatose 3 days after treatment. {H}e slowly deteriorated over 5 weeks and died at 54 days after the anthelminthic treatment, probably as a result of a secondary skin or pulmonary infection exacerbated by malnutrition. {T}he major pre- and post-autopsy findings included the presence of high loads of {L}oa loa, positivity for {P}lasmodium, the presence of a longstanding respiratory condition, and vascular pathology in the brain. {T}he central nervous system lesions have similarities with those described in previously reported cases of {L}oa loa-associated death following diethylcarbamazine treatment.}, keywords = {}, booktitle = {}, journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene}, volume = {78}, numero = {4}, pages = {546--551}, ISSN = {0002-9637}, year = {2008}, URL = {https://www.documentation.ird.fr/hor/fdi:010043757}, }