@article{fdi:010042985,
  title = {{L}oiasis : the individual factors associated with the presence of microfilaraemia},
  author = {{P}ion, {S}{\'e}bastien and {D}emanou, {M}. and {O}udin, {B}. and {B}oussinesq, {M}ichel},
  editor = {},
  language = {{ENG}},
  abstract = {{N}o microfilariae are detectable in a significant percentage of those infected with the filarial worm {L}oa loa. {W}hile the probability of an infected individual becoming microfilaraemic is known to increase with age, the mechanisms underlying this trend are not well understood. {E}pidemiological data from an endemic village in central {C}ameroon were therefore explored, in an attempt to determine if, after taking into account any history of filaricidal treatment, the presence of {L}oa microfilaraemia in an individual was related to his/her gender, age, and/or exposure to the human-infective larvae of the parasite. {A}n index of exposure, based on the monthly transmission potentials of the {C}hrysops in each of the main types of vegetation in a village and on the activity schedule of each inhabitant of the village, was developed. {T}he results of the data analysis confirm that the acquisition of microfilaraemia is gender-dependent (males generally being more likely to be microfilaraemic than females), and indicate that, in males, a high level of exposure to infective larvae determines the shift from amicrofilaraemic to microfilaraemic status. {T}hey also indicate that filaricidal treatments have a long-lasting suppressive effect on {L}oa microfilaraemia, an observation that may have important implications for any strategy to limit the risk of {L}oa-associated encephalopathy following ivermectin treatment.},
  keywords = {},
  booktitle = {},
  journal = {{A}nnals of {T}ropical {M}edicine and {P}arasitology},
  volume = {99},
  numero = {5},
  pages = {491--500},
  ISSN = {0003-4983},
  year = {2005},
  DOI = {10.1179/136485905{X}51300},
  URL = {https://www.documentation.ird.fr/hor/fdi:010042985},
}