@article{fdi:010042696, title = {{P}opulation structure of the malaria vector {A}nopheles moucheti in the equatorial forest region of {A}frica - art. no. 120}, author = {{A}ntonio-{N}kondjio, {C}. and {N}do, {C}. and {K}engne, {P}ierre and {M}ukwaya, {L}. and {A}wono-{A}mbene, {P}. and {F}ontenille, {D}idier and {S}imard, {F}r{\'e}d{\'e}ric}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {A}nopheles moucheti is a major malaria vector in forested areas of {A}frica. {H}owever, despite its important epidemiological role, it remains poorly known and insufficiently studied. {H}ere, levels of genetic differentiation were estimated between different {A}. moucheti populations sampled throughout its distribution range in {C}entral {A}frica. {M}ethods: {P}olymorphism at ten microsatellite markers was compared in mosquitoes sampled in {C}ameroon, the {D}emocratic {R}epublic of {C}ongo and an island on {L}ake {V}ictoria in {U}ganda. {M}icrosatellite data were used to estimate genetic diversity within populations, their relative long-term effective population size, and the level of genetic differentiation between them. {R}esults: {A}ll specimens collected in {T}sakalakuku ({D}emocratic {R}epublic of {C}ongo) were identified as {A}. m. bervoetsi while other samples consisted of {A}. m. moucheti. {S}uccessful amplification was obtained at all microsatellite loci within all {A}. m. moucheti samples while only six loci amplified in {A}. m. bervoetsi. {A}llelic richness and heterozygosity were high for all populations except the island population of {U}ganda and {A}. m. bervoetsi. {H}igh levels of genetic differentiation were recorded between {A}. m. bervoetsi and each {A}. m. moucheti sample as well as between the island population of {A}. m. moucheti and mainland populations. {S}ignificant isolation by distance was evidenced between mainland populations. {C}onclusion: {H}igh levels of genetic differentiation supports complete speciation of {A}. m. bervoetsi which should henceforth be recognized as a full species and named {A}. bervoetsi. {I}solation by distance is the main force driving differentiation between mainland populations of {A}. m. moucheti. {G}enetically and geographically isolated populations exist on {L}ake {V}ictoria islands, which might serve as relevant field sites for evaluation of innovative vector control strategies.}, keywords = {}, booktitle = {}, journal = {{M}alaria {J}ournal}, volume = {7}, numero = {120}, pages = {4}, ISSN = {1475-2875}, year = {2008}, DOI = {10.1186/1475-2875-7-120}, URL = {https://www.documentation.ird.fr/hor/fdi:010042696}, }