@article{fdi:010042661,
  title = {{B}ehind the scene, something else is pulling the strings : emphasizing parasitic manipulation in vector-borne diseases},
  author = {{L}ef{\`e}vre, {T}hierry and {T}homas, {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{M}erging the field of epidemiology with those of evolutionary and behavioural ecology can generate considerable fundamental knowledge, as well as help to guide public health policies. {A}n attempt is made here to integrate these disciplines by focusing on parasitic manipulation in vector-borne diseases. {P}arasitic manipulation is a fascinating strategy of transmission which occurs when a parasite alters phenotypic trait(s) of its host in a way that enhances its probability of transmission. {V}ector-borne parasites are responsible for many of the most harmful diseases affecting humans, and thus represent public health priority. {I}t has been shown for several decades that viruses, bacteria and protozoa can alter important features of their arthropod vector and vertebrate host in a way that increases their probability of transmission. {H}ere, we review these changes, including, the feeding behaviour, survival and immune system of the vector, as well as attraction, defensive behaviour, blood characterictics and immune system of the vertebrate host. {B}ased on the classic measure of vector-borne disease transmission {R}-0, additional changes, such as, vertebrate host choice by infected vectors or parasite development duration in the vector are expected. {R}eported or expected phenotypic changes are discussed in terms of costs and benefits to the parasite, its vector, and the vertebrate host. {I}ntroducing the parasitic manipulation concept into vector-borne diseases clearly highlights fruitful avenues not only for fundamental research, but also for developing strategies for disease control.},
  keywords = {{P}arasitic manipulation ; {V}ector-borne diseases},
  booktitle = {},
  journal = {{I}nfection, {G}enetics and {E}volution},
  volume = {8},
  numero = {4},
  pages = {504--519},
  ISSN = {1567-1348},
  year = {2008},
  DOI = {10.1016/j.meegid.2007.05.008},
  URL = {https://www.documentation.ird.fr/hor/fdi:010042661},
}