Djogbénou Luc auteur aut IRD Dabiré R. auteur aut IRD Diabaté A. auteur aut IRD Kengne Pierre auteur aut IRD Akogbéto M. auteur aut IRD Hougard Jean-Marc auteur aut IRD Chandre Fabrice auteur aut IRD text journalArticle eng text/pdf reformatted digital access Resistance of Anopheles gambiae to organophosphate and carbamate insecticides was first reported in Cote d'Ivoire, West Africa. Subsequent studies revealed that it resulted from a single point mutation in the oxyanion hole of the acetycholinesterase enzyme (ace-1(R) mutation). We investigated the distribution and prevalence of the ace-1(R) mutation in An. gambiae s.l. populations from seven locations in south-western Burkina Faso. The ace-1(R) mutation was found in both M and S molecular forms of An. gambiae s.s., but it was absent in An. arabiensis. Its frequency ranged from 0.25 to 0.5 in S form and 0.04 to 0.13 in M form, though they were sympatric. The lack of homozygous resistance indicated a strong genetic cost associated with the mutation. These data suggest that organophosphate and carbamate resistance conferred by target site insensitivity is spreading in populations of An. gambiae s.s. from West Africa. specialized 052 78 2 298-302 2008 0002-9637 https://www.documentation.ird.fr/hor/fdi:010042492 0002-9637 [F B010042492] https://www.documentation.ird.fr/hor/fdi:010042492 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-08/010042492.pdf IRD - Base Horizon / Pleins textes 2008-03-31 2020-09-17 fdi:010042492 fre