@article{fdi:010042480,
  title = {{P}lants, {MEN} and {SIN}},
  author = {{B}edhomme, {M}. and {J}ouannic, {S}tefan and {C}hampion, {A}ntony and {S}imanis, {V}. and {H}enry, {Y}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}n fission yeast, the onset of septation is signalled through the septum initiation network ({SIN}) signaling pathway. {S}imilarly, in budding yeast the onset of budding is signalled through the mitotic exit network ({MEN}) pathway. {W}e previously characterized in {A}rabidopsis signaling elements ({GTP}ases, kinases) closely related to the core elements (spg 1p/{TEM}1p, cdc7p/{CDC}15p) of the {SIN} and {MEN} pathways. {O}ur first results suggested that a plant signaling pathway must be used to coordinate mitotic exit with cytokinesis. {T}his review questioned the value of such an hypothesis in a multicellular organism. {T}he core elements ({G}-protein, kinase) of the {SIN} and {MEN} pathways were only detected in fungi, plants and {M}ycetozoa. {W}e also noticed that {A}t{SGP} {GTP}ase and {A}t{MAP}3{K}epsilon kinase revealed two paralogues in {A}rabidopsis. {A}lthough {A}rabidopsis genes complement fission yeast mutants, and {A}rabidopsis proteins interact with fission yeast proteins, plants do not use these core elements to coordinate the termination of cell division with cytokinesis. {T}ranscriptional regulation and expression data suggest a function for the plant {SIN}-like elements in the control of cell type specification. {E}xploring the evolutionary conservation of an ancient signaling pathway provides evidence that evolution has recycled regulatory elements for elaborating a new signaling avenue.},
  keywords = {},
  booktitle = {},
  journal = {{P}lant {P}hysiology and {B}iochemistry},
  volume = {46},
  numero = {1},
  pages = {1--10},
  ISSN = {0981-9428},
  year = {2008},
  DOI = {10.1016/j.plaphy.2007.10.010},
  URL = {https://www.documentation.ird.fr/hor/fdi:010042480},
}