@article{fdi:010042254,
  title = {{S}tructural organization of an encephalitic human isolate of {B}anna virus (genus {S}eadornavirus, family {R}eoviridae)},
  author = {{J}aafar, {F}.{M}. and {A}ttoui, {H}. and {M}ertens, {P}.{P}.{C}. and de {M}icco, {P}. and {L}amballerie, {X}avier de},
  editor = {},
  language = {{ENG}},
  abstract = {{B}anna virus ({BAV}) is the type species of the genus {S}eadornavirus within the family {R}eoviridae. {T}he {C}hinese {BAV} isolate ({BAV}-{C}h), which causes encephalitis in humans, was shown to have a structural organization and particle morphology reminiscent of that of rotaviruses, with fibre proteins projecting from the surface of the particle. {I}ntact {BAV}-{C}h virus particles contain seven structural proteins, two of which ({VP}4 and {VP}9) form the outer coat. {T}he inner (core) particles contain five additional proteins ({VP}1, {VP}2, {VP}3, {VP}8 and {VP}10) and are 'non-turreted', with a relatively smooth surface appearance. {VP}2 is the '{T} = 2' protein that forms the innermost 'subcore' layer, whilst {VP}8 is the '{T} = 13' protein forming the core-surface layer. {S}equence comparisons indicate that {BAV} {VP}9 and {VP}1 0 are equivalent to the {VP}8* and {VP}5* domains, respectively, of rotavirus outer-coat protein {VP}4 ({G}en{B}ank accession no. {P}12976). {VP}9 has also been shown to be responsible for virus attachment to the host-cell surface and may be involved in internalization. {T}hese similarities reveal a previously unreported genetic link between the genera {R}otavirus and {S}eadornavirus, although the expression of {BAV} {VP}9 and {VP}1 0 from two separate genome segments, rather than by the proteolytic cleavage of a single gene product (as seen in rotavirus {VP}4), suggests a significant evolutionary jump between the members of these two genera.},
  keywords = {},
  booktitle = {},
  journal = {{J}ournal of {G}eneral {V}irology},
  volume = {86 {P}art 4},
  numero = {},
  pages = {1147--1157},
  ISSN = {0022-1317},
  year = {2005},
  DOI = {10.1099/vir.0.80578-0},
  URL = {https://www.documentation.ird.fr/hor/fdi:010042254},
}