@article{fdi:010042171,
  title = {{G}ene flow between chromosomal forms of the malaria vector {A}nopheles funestus in {C}ameroon, {C}entral {A}frica, and its relevance in malaria fighting},
  author = {{C}ohuet, {A}nna and {D}ia, {I}. and {S}imard, {F}r{\'e}d{\'e}ric and {R}aymond, {M}. and {R}ousset, {F}. and {A}ntonio {N}kondjio, {C}. and {A}wono {A}mbene, {P}.{H}. and {W}ondji, {C}.{S}. and {F}ontenille, {D}idier},
  editor = {},
  language = {{ENG}},
  abstract = {{K}nowledge of population structure in a major vector species is fundamental to an understanding of malaria epidemiology and becomes crucial in the context of genetic control strategies that are being dcvelopcd. {D}espite its epidemiological importance, the major {A}frican malaria vector {A}nopheles funestus has received far less attention than members of the {A}nopheles gambiae complex. {P}revious chromosomal data have shown a high degree of structuring within populations from {W}est {A}frica and have led to the characterization of two chromosomal forms, "{K}iribina" and "{F}olonzo." {I}n {C}entral {A}frica, few data were available. {W}e thus undertook assessment of genetic structure of {A}n. funestus populations from {C}ameroon rising chromosomal inversions and microsatellite markers. {M}icrosatellite markers revealed no particular departure from panmixia within each local population and a genetic structure consistent with isolation by distance. {H}owever, cytogenetic studies demonstrated high levels of chromosomal heterogeneity, both within and between populations. {D}istribution of chromosomal inversions was not random and a cline of frequency was observed, according to ecotypic conditions. {S}trong deficiency of heterokaryotypes was found in certain localities in the transition area, indicating a subdivision of {A}n.funestus in chromosomal forms. {A}n. funestus microsatellite genetic markers located within the breakpoints of inversions are not differentiated in populations, whereas in {A}n. gambiae inversions can affect gene flow at marker loci. {T}hese results are relevant to strategies for control of malaria by introduction of transgenes into populations of vectors.},
  keywords = {},
  booktitle = {},
  journal = {{G}enetics},
  volume = {169},
  numero = {1},
  pages = {301--311},
  ISSN = {0016-6731},
  year = {2005},
  DOI = {10.1534/genetics.103.025031},
  URL = {https://www.documentation.ird.fr/hor/fdi:010042171},
}