@article{fdi:010041526, title = {{S}usceptibility of {A}edes aegypti larvae to the insecticide temephos in the {F}ederal {D}istrict, {B}razil}, author = {de {C}arvalho, {M}.{D}.{S}. and {C}aldas, {E}.{D}. and {D}{\'e}gallier, {N}icolas and {V}ilarinhos, {P}.{D}.{T}. and {D}e {S}ouza, {L}. and {A}melia, {M}. and {Y}oshizawa, {C}. and {K}nox, {M}. {B}. and {D}e {O}liveira, {C}.}, editor = {}, language = {{ENG}}, abstract = {{O}bjective: {T}o study the susceptibility status of {A}edes aegypti to the organophosphate insecticide temephos. {M}ethods: {S}amples of {A}e. aegypti larvae were obtained, using ovitraps, from eight cities of the {F}ederal {D}istrict, central {B}razil, in 2000 and 2001. {L}arvae were submitted to the diagnostic dose of 0.012 mg/l temephos, as recommended by standard {W}orld {H}ealth {O}rganization methodology. {F}ield populations were tested in parallel with reference strains {R}ockefeller and {DIVAL}, from the {E}nvironmental {S}urveillance {D}irectory ({DIVAL}) insectary. {T}he concentration and purity of temephos solutions were verified by gas chromatography. {C}orrelation calculations were performed using {S}tat{V}iew - {SAS} {I}nstitute {I}nc., version 5. {S}tudent's t test was used for detecting differences in susceptibility, with significance levels of alpha=0.05. {R}esults: {I}n 2000, {A}e. aegypti larvae populations from {T}aguatinga, {G}uara, and {N}ucleo {B}andeirante showed resistance to temephos, with mortality ranging from 54.1 to 63.4%. {T}he populations from {G}ama, {P}lanaltina, and {S}obradinho showed altered levels of susceptibility (mortality ranging from 83.6 to 92.8%). {T}he population from {C}eilandia was the only susceptible one, with 98% mortality. {I}n 2001, all populations tested were resistant (44.4 to 66.4% mortality). {N}o significant correlation was found between the susceptibility of populations and the distance between the cities of origin, or the amount of insecticide applied in the years preceding the study. {C}onclusions: {A}e. aegypti susceptibility to temephos is changing in the {F}ederal {D}istrict. {I}t is essential to continue monitoring the resistance of this vector to insecticides in order to ensure the efficiency of programs aimed at vector control and at the protection of human health.}, keywords = {aedes ; {T}emephos ; insecticide resistance ; vector control ; insect vectors ; {BRESIL}}, booktitle = {}, journal = {{R}evista {D}e {S}aude {P}ublica}, volume = {38}, numero = {5}, pages = {623--629}, ISSN = {0034-8910}, year = {2004}, URL = {https://www.documentation.ird.fr/hor/fdi:010041526}, }