@article{fdi:010040966,
  title = {{C}haracterization of an old complex circulating recombinant form, {CRF}27_cpx, originating from the democratic republic of {C}ongo ({DRC}) and circulating in {F}rance},
  author = {{V}idal, {N}icole and {F}range, {P}. and {C}haix, {M}. {L}. and {M}ulanga, {C}laire and {L}epira, {F}. and {B}azepeo, {S}. {E}. and {G}oujard, {C}. and {M}eyer, {L}. and {R}ouzioux, {C}. and {D}elaporte, {E}ric and {P}eeters, {M}artine},
  editor = {},
  language = {{ENG}},
  abstract = {{F}ull-length genomes were characterized for two samples, 02{CD}-{LBR}024 from the {D}emocratic {R}epublic of {C}ongo ({DRC}) and 04{FR}-{CD}-{KZS} from {F}rance, that formed a separate subcluster with a previously characterized env subtype {E} isolate from {DRC} with a recombinant structure different from {CRF}01-{AE}. {S}ince the three viruses are clearly epidemiologically unlinked and share the same complex recombinant structure, they represent a circulating recombinant form, designated as {CRF}27-cpx. {T}he recombination pattern involves six different {HIV}-1 subtypes ({A}, {E}, {G}, {H}, {J}, and {K}) and a small unclassified fragment. {T}he genetic distances are relatively high, indicating that {CRF}27-cpx evolved over a long time. {T}heir prevalence is low (0.75%) and remained stable over time in the {DRC}. {T}he existence of the 04{FR}. {CD}. {KZS} virus, in a patient who recently seroconverted in {F}rance, confirmed that these strains now circulate outside the {DRC}. {C}ontinuous monitoring of {HIV}-1 strains thus remains important to allow early identification of the introduction of new variants.},
  keywords = {},
  booktitle = {},
  journal = {{A}ids {R}esearch and {H}uman {R}etroviruses},
  volume = {24},
  numero = {2},
  pages = {315--321},
  ISSN = {0889-2229},
  year = {2008},
  DOI = {10.1089/aid.2007.0241},
  URL = {https://www.documentation.ird.fr/hor/fdi:010040966},
}