@article{fdi:010040907, title = {{G}enetic population structure of {A}nopheles gambiae in {E}quatorial {G}uinea - art. no. 137}, author = {{M}oreno, {M}. and {S}algueiro, {P}. and {V}icente, {J}. {L}. and {C}ano, {J}. and {B}erzosa, {P}. {J}. and de {L}ucio, {A}. and {S}imard, {F}r{\'e}d{\'e}ric and {C}accone, {A}. and {D}o {R}osario, {V}. {E}. and {P}into, {J}. and {B}enito, {A}.}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {P}atterns of genetic structure among mosquito vector populations in islands have received particular attention as these are considered potentially suitable sites for experimental trials on transgenic-based malaria control strategies. {I}n this study, levels of genetic differentiation have been estimated between populations of {A}nopheles gambiae s.s.from the islands of {B}ioko and {A}nnobon, and from continental {E}quatorial {G}uinea ({EG}) and {G}abon. {M}ethods: {G}enotyping of 11 microsatellite loci located in chromosome 3 was performed in three island samples (two in {B}ioko and one in {A}nnobon) and three mainland samples (two in {EG} and one in {G}abon). {F}our samples belonged to the {M} molecular form and two to the {S}-form. {M}icrosatellite data was used to estimate genetic diversity parameters, perform demographic equilibrium tests and analyse population differentiation. {R}esults: {H}igh levels of genetic differentiation were found between the more geographically remote island of {A}nnobon and the continent, contrasting with the shallow differentiation between {B}ioko island, closest to mainland, and continental localities. {I}n {B}ioko, differentiation between {M} and {S} forms was higher than that observed between island and mainland samples of the same molecular form. {C}onclusion: {T}he observed patterns of population structure seem to be governed by the presence of both physical (the ocean) and biological (the {M}-{S} form discontinuity) barriers to gene flow. {T}he significant degree of genetic isolation between {M} and {S} forms detected by microsatellite loci located outside the "genomic islands" of speciation identified in {A}. gambiae s.s. further supports the hypothesis of on-going incipient speciation within this species. {T}he implications of these findings regarding vector control strategies are discussed.}, keywords = {}, booktitle = {}, journal = {{M}alaria {J}ournal}, volume = {6}, numero = {}, pages = {{NIL}_1--{NIL}_10}, ISSN = {1475-2875}, year = {2007}, DOI = {10.1186/1475-2875-6-137}, URL = {https://www.documentation.ird.fr/hor/fdi:010040907}, }