@article{fdi:010040789,
  title = {{C}linical trial of an {F}(ab')(2) polyvalent equine antivenom for {A}frican snake bites in {B}enin},
  author = {{C}hippaux, {J}ean-{P}hilippe and {M}assougbodji, {A}. and {S}tock, {R}. {P}. and {A}lagon, {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{W}e report the results of a trial designed to measure the safety and efficacy of {A}frican {A}ntivipmyn(({R})), a new freeze-dried polyvalent equine {F}(ab')(2)-based antivenom. {W}e tested 289 envenomations. {A}fter treatment, 19% of treated patients had undesirable events, all benign. {A} possible adverse effect was attributed to this antivenom in 11% of the patients. {B}leeding was observed in 48% of the patients; it stopped within 2 hours after treatment with antivenom in 60% of the patients. {B}lood incoagulability was observed in 80% of the patients. {R}estoration of coagulation was attained within 4 hours in 60% of the patients. {N}ine patients died; 6 arrived at the hospital in the final stage of complications and 5 arrived at the hospital more than 60 hours after the bite. {T}he value of blood coagulation tests in diagnosis of envenomation and bleeding as an indicator of renewal of treatment are emphasized.},
  keywords = {},
  booktitle = {},
  journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene},
  volume = {77},
  numero = {3},
  pages = {538--546},
  ISSN = {0002-9637},
  year = {2007},
  URL = {https://www.documentation.ird.fr/hor/fdi:010040789},
}