@article{fdi:010040787, title = {{I}mpact of intermittent preventive anti-malarial treatment on the growth and nutritional status of preschool children in rural {S}enegal ({W}est africa)}, author = {{N}tab, {B}althazar and {C}iss{\'e}, {B}adara and {B}oulanger, {D}enis and {S}okhna, {C}heikh and {T}argett, {G}. and {L}ines, {J}. and {A}lexander, {N}. and {T}rape, {J}ean-{F}ran{\c{c}}ois and {S}imondon, {F}ran{\c{c}}ois and {G}reenwood, {B}. {M}. and {S}imondon, {K}irsten}, editor = {}, language = {{ENG}}, abstract = {{N}egative consequences of malaria might account for seasonality in nutritional status in children in the {S}ahel. {W}e report the impact of a randomized, double-blind, placebo-con trolled trial of seasonal intermittent preventive anti-malarial treatment on growth and nutritional status in 1,063 {S}enegalese preschool children. {A} combination of artesunate and sulfadoxine-pyrimethamine was given monthly from {S}eptember to {N}ovember. {I}n the intervention arm, mean weight gain was significantly greater (122.9 +/- 340 versus 42.9 +/- 344 [{SD}] g/mo, {P} < 0.0001) and losses in triceps and subscapular skinfold measurements were less (-0.39 +/- 1.01 versus -0.66 +/- 1.01 mm/mo, and -0.15 +/- 0.64 versus -0.36 +/- 0.62 mm/mo, respectively, {P} < 0.0001 for both). {T}here was no difference in height increments. {T}he prevalence of wasting increased significantly in the control arm (4.6% before versus 9.5% after, {P} < 0.0001), but remained constant in intervention children: 5.6% versus 7.0% ({P} = 0.62). {T}he prevention of malaria would improve child nutritional status in areas with seasonal transmission.}, keywords = {}, booktitle = {}, journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene}, volume = {77}, numero = {3}, pages = {411--417}, ISSN = {0002-9637}, year = {2007}, URL = {https://www.documentation.ird.fr/hor/fdi:010040787}, }