@article{fdi:010040781, title = {{A}mazonian plants from {P}eru used by {Q}uechua and {M}estizo to treat malaria with evaluation of their activity}, author = {{R}oumy, {V}. and {G}arcia {P}izango, {G}. and {G}utierrez {C}hoquevilca, {A}. {L}. and {R}uiz, {L}. and {J}ullian, {V}al{\'e}rie and {W}interton, {P}. and {F}abre, {N}. and {M}oulis, {C}. and {V}alentin, {A}.}, editor = {}, language = {{ENG}}, abstract = {{I}ndigenous {Q}uechua and {M}estizo populations from distinct areas in {L}oreto, {P}eru, were interviewed about traditional medication for the treatment of malaria. {A}n ethnographic survey concerning the native theory of illness aetiology in the specific case of malaria permitted the elaboration of an efficient ethnopharmacological enquiry. {T}he survey took place on three main zones corresponding to villages on the {N}apo and the {P}astaza rivers (for the {Q}uechua), and in the surroundings of {I}quitos (for the {M}estizos) and led to the collection of 14 plants. {S}erial extractions in hexane, dichloromethane, and methanol were performed on the different parts of the plants collected. {T}he extracts were then tested for antiplasmodial activity in vitro. {S}even plants displayed antiplasmodial activity ({IC}50 from 2 to 25 mu g/m{L}) and usually low cytotoxicity, indicating their antiplasmodial specificity. {T}he results give scientific validation to the traditional medical knowledge of {Q}uechua and {M}estizo populations from {L}oreto and confirm a source of potentially active plants.}, keywords = {malaria ; {L}oreto ; in vitro screening ; {Q}uechua ; ethnomedicine ; {P}eru}, booktitle = {}, journal = {{J}ournal of {E}thnopharmacology}, volume = {112}, numero = {3}, pages = {482--489}, ISSN = {0378-8741}, year = {2007}, DOI = {10.1016/j.jep.2007.04.009}, URL = {https://www.documentation.ird.fr/hor/fdi:010040781}, }