Study of the efficacy of the black stone on envenomation by snake bite in the murine model Chippaux Jean-Philippe auteur aut IRD Ramos Cerrillo B. auteur aut IRD Stock R. P. auteur aut IRD text journalArticle eng text/pdf born digital access The black stone (BS) has been used since antiquity to treat envenomations. Since no actual clinical trial has ever been performed we used an experimental approach to evaluate its efficacy against the venoms of Bitis arietans, Echis ocellatus and Naja nigricollis. Local application of BS after intramuscular venom injection had no demonstrable effect on the outcome of envenomationa and it did not change the LD50 of B. arietans venom. Our results show that, contrary to widespread belief, no efficacy to treat envenomation may be expected of the BS. specialized snake bite envenomation black stone traditional medicine 050 Toxicon 49 5 717-720 2007 0041-0101 https://www.documentation.ird.fr/hor/fdi:010037968 10.1016/j.toxicon.2006.11.002 0041-0101 [F B010037968] https://www.documentation.ird.fr/hor/fdi:010037968 https://www.documentation.ird.fr/intranet/publi/2007/06/010037968.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2007-06-28 2017-08-23 fdi:010037968 fre