%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Boccolini, D. %A Carrara, G. C. %A Dia, I. %A Fortes, F. %A Cani, P. J. %A Costantini, Carlo %T Chromosomal differentiation of Anopheles funestus from Luanda and Huambo Provinces, western and central Angola %D 2005 %L fdi:010037807 %G ENG %J American Journal of Tropical Medicine and Hygiene %@ 0002-9637 %M CC:0002343539-0015 %N 6 %P 1071-1076 %U https://www.documentation.ird.fr/hor/fdi:010037807 %> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-08/010037807.pdf %V 73 %W Horizon (IRD) %X The chromosomal polymorphism of Anopheles funestus sensu stricto from Angola was analyzed from indoor-resting samples collected in 11 peri-urban and rural sites of the Luanda and Huambo Provinces, which are > 450 km apart and have distinct eco-climatic conditions. Five polymorphic paracentric inversions were observed (scored chromatids range = 202 to 248): 2Ra, 2Rh, 3Ra, 3Rb, and 3La. Inversions 3Rb and 31-a were highly polymorphic; the 2Ra and 3Ra arrangements were absent in Luanda. No significant departures from Hardy-Weinberg and linkage equilibria were found at the locality, commune, or province level (sites <= 50 kin from each other), indicating panmixia in each locale. Pooling the Luanda and Huambo samples produced a Wahlund effect, with significant levels of genetic differentiation suggestive of restrictions to gene flow due to geographic distance. The observation that differentiation was limited to inversions 2Ra and 3Ra can also be interpreted as divergent selection acting on these chromosomal regions between populations from the two provinces. %$ 052