@article{fdi:010037774, title = {{E}valuation of the diethylcarbamazine patch to evaluate onchocerciasis endemicity in {C}entral {A}frica}, author = {{O}zoh, {G}. and {B}oussinesq, {M}ichel and {B}issek, {A}czk and {K}obangue, {L}. and {K}ombila, {M}. and {M}bina, {J}. {R}. {M}. and {E}nyong, {P}. and {N}oma, {M}. and {S}eketeli, {A}. and {F}obi, {G}.}, editor = {}, language = {{ENG}}, abstract = {{OBJECTIVE} {A}s part of a baseline data collection for assessing the impact of the {A}frican {P}rogramme for {O}nchocerciasis {C}ontrol, to evaluate the diethylcarbamazine ({DEC}) patch test in determining the endemicity of onchocerciasis. {METHOD} {A} total of 226 untreated children aged 3-5, living in four selected endemic foci, in {C}ameroon, {G}abon and {C}entral {A}frican {R}epublic, were tested. {O}bserved graded skin reactions to the patch were analysed and compared with the prevalence of onchocercal nodules and reactive skin disease in the corresponding community. {RESULTS} {T}he proportion of children who tested positive ranged from 25.0% to 77.1%. {T}he values were closely correlated with the prevalence of nodules, i.e. the level of endemicity for onchocerciasis. {CONCLUSION} {T}he {DEC} patch test, which has been so far used only in {W}est {A}frican foci of onchocerciasis, can also constitute a valuable tool to evaluate the levels of endemicity of onchocerciasis in {C}entral {A}frica, and to follow-up the intensity of transmission of {O}nchocerca volvulus.}, keywords = {onchocerciasis ; diethylcarbamazine patch test ; epidemiology ; diagnosis ; {C}entral {A}frica ; {A}frican {P}rogramme for {O}nchocerciasis {C}ontrol}, booktitle = {}, journal = {{T}ropical {M}edicine and {I}nternational {H}ealth}, volume = {12}, numero = {1}, pages = {123--129}, ISSN = {1360-2276}, year = {2007}, DOI = {10.1111/j.1365-3156.2006.01750.x}, URL = {https://www.documentation.ird.fr/hor/fdi:010037774}, }