@article{fdi:010037770,
  title = {{A}ntischistosomal efficacy of artesunate combination therapies administered as curative treatments for malaria attacks},
  author = {{B}oulanger, {D}enis and {D}ieng, {Y}. and {C}iss{\'e}, {B}adara and {R}emou{\'e}, {F}ranck and {C}apuano, {F}r{\'e}d{\'e}ric and {D}ieme, {J}ean-{L}ouis and {N}diaye, {T}of{\`e}ne and {S}okhna, {C}heikh and {T}rape, {J}ean-{F}ran{\c{c}}ois and {G}reenwood, {B}. and {S}imondon, {F}ran{\c{c}}ois},
  editor = {},
  language = {{ENG}},
  abstract = {{A}rtesunate is a highly effective antimalarial. and there is some evidence that it is also active against schistosome infections. {W}e therefore investigated whether treatment with artesunate of acute malaria in {S}enegalese children had an impact on their level of infection with {S}chistosoma haematobium. {T}wenty-seven children who were entered into a clinical trial of antimalaria treatment were excreting {S}. haematobium eggs in their urine on the day of treatment. {F}ifteen children received a combination of a single dose of sulfadoxine/pyrimethamine together with three daily doses of artesunate (4 mg/kg); the remaining 12 children received three daily doses of amodiaquine and artesunate. {T}he overall cure rate and reduction in the mean number of excreted eggs at 28 days post treatment were 92.6% and 94.5%, respectively. {O}ur findings indicate that artesunate, in addition to being a very effective treatment for uncomplicated malaria, can also sharply reduce the {S}. haematobium loads harboured by pre-school {A}frican children. ({C}) 2006 {P}ublished by {E}lsevier {L}td on behalf of {R}oyal {S}ociety of {T}ropical {M}edicine and {H}ygiene.},
  keywords = {malaria ; {P}lasmodium falciparum ; {S}chistosoma haematobium ; artesunate ; artemisinin based ; combination therapy ; {S}enegal},
  booktitle = {},
  journal = {{T}ransactions of the {R}oyal {S}ociety of {T}ropical {M}edicine and {H}ygiene},
  volume = {101},
  numero = {2},
  pages = {113--116},
  ISSN = {0035-9203},
  year = {2007},
  DOI = {10.1016/j.trstmh.2006.03.003},
  URL = {https://www.documentation.ird.fr/hor/fdi:010037770},
}