@article{fdi:010037764,
  title = {{P}roteome analysis of plant-virus interactome - {C}omprehensive data for virus multiplication inside their hosts},
  author = {{B}rizard, {J}ean-{P}aul and {C}arapito, {C}. and {D}elalande, {F}. and {V}an {D}orsselaer, {A}. and {B}rugidou, {C}hristophe},
  editor = {},
  language = {{ENG}},
  abstract = {{K}nown host-parasite molecular interactions are widespread among parasite families, but these interactions have to be particularly large considering that viruses generally encode few proteins. {A}lthough some particular virus-host interactions are well described, no global study has yet shown multiple and simultaneous interactions in a host-parasite biological system. {T}o prove that these multiple interactions occur in biological conditions, the complexes formed by a plant virus ( rice yellow mottle virus) and the proteins of its natural host ( rice) were extracted and purified from infected tissue sample. {R}emarkably mass spectrometry permitted the identification of a large number of proteins from the complexes that are involved in different functions not encoded by the virus but probably essential for its biological life cycle. {T}his recruiting of proteins was strongly confirmed by the repetition of experiments using different pairs of virus-host and the use of high salt concentration to extract the complexes. {W}e mainly identified proteins involved in plant defense, metabolism, translation, and protein synthesis and some proteins involved in transport. {T}his study demonstrates that viruses are able to recruit many proteins from their hosts to ensure their development. {A}mong different pairs of virus-host, similar protein functions were identified suggesting a particular importance of these proteins for viruses. {T}he identification of particular paralog proteins among multigenic families suggests the high specificity of the recruiting for some protein functions.},
  keywords = {},
  booktitle = {},
  journal = {{M}olecular and {C}ellular {P}roteomics},
  volume = {5},
  numero = {12},
  pages = {2279--2297},
  ISSN = {1535-9476},
  year = {2006},
  DOI = {10.1074/mcp.{M}600173-{MCP}200},
  URL = {https://www.documentation.ird.fr/hor/fdi:010037764},
}