@article{fdi:010037757, title = {{C}yclical transmission of {T}rypanosoma brucei gambiense in {G}lossina palpalis gambiensis displays great differences among field isolates}, author = {{R}avel, {S}ophie and {P}atrel, {D}elphine and {K}offi, {M}athurin and {J}amonneau, {V}incent and {C}uny, {G}{\'e}rard}, editor = {}, language = {{ENG}}, abstract = {{S}ix sets of teneral {G}lossina palpalis gambiensis ({D}iptera: {G}lossinidae) were fed on mice infected with six different isolates of {T}hpanosoma brucei gambiense (each mouse was infected with one of the isolates), previously isolated from patients in the sleeping sickness focus of {B}onon, {C}ote d'{I}voire and in {M}akoua, {C}ongo. {A}ll the tsetse flies were dissected 42 days post-infection and midgut and salivary glands were examined for trypanosomes by microscopical examination. {N}o infection was observed with the reference stock whereas each of the five recently isolated trypanosome isolates was able to infect tsetse flies, with rates of infection varying between 9.7 and 18.2% depending on the isolate. {T}hree isolates displayed only immature infections with 9.7, 17.3 and 18% of the flies showing trypanosomes in their midgut. {O}ne isolate gave both immature (12.1%) and mature infections (6.1%). {F}inally, the last isolate involved only mature infections in 9.7% of the {G}lossina species examined. {T}hese substantial differences in the cyclical transmission of {T} b. gambiense in the same fly species could have important implications for the epidemiology of the transmission of {H}uman {A}frican {T}rypanosomiasis.}, keywords = {{T}rypanosoma brucei gambiense ; {G}lossina palpalis gambiensis ; field isolates ; mature infections ; vectorial competence ; {HAT}}, booktitle = {}, journal = {{A}cta {T}ropica}, volume = {100}, numero = {1-2}, pages = {151--155}, ISSN = {0001-706{X}}, year = {2006}, DOI = {10.1016/j.actatropica.2006.09.011}, URL = {https://www.documentation.ird.fr/hor/fdi:010037757}, }