@article{fdi:010037641, title = {{E}fficacy of bifenthrin-impregnated bednets against {A}nopheles funestus and pyrethroid-resistant {A}nopheles gambiae in {N}orth {C}ameroon - art. no. 77}, author = {{C}houaibou, {M}ouhamadou and {S}imard, {F}r{\'e}d{\'e}ric and {C}handre, {F}abrice and {E}tang, {J}. and {D}arriet, {F}r{\'e}d{\'e}ric and {H}ougard, {J}ean-{M}arc}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {R}ecent field studies indicated that insecticide- treated bednets ( {ITN}s) maintain their efficacy despite a high frequency of the knock- down resistance ( kdr) gene in {A}nopheles gambiae populations. {I}t was essential to evaluate {ITN}s efficacy in areas with metabolic- based resistance. {M}ethods: {B}ifenthrin was used in this experiment because it is considered a promising candidate for bednets impregnation. {N}ets were treated at 50 mg/ m(2), a dose that has high insecticidal activity on kdr mosquitoes and at 5 mg/ m2, a dose that kills 95% of susceptible mosquitoes under laboratory conditions with 3 minutes exposure. {B}ednets were holed to mimic physical damage. {T}he trial was conducted in three experimental huts from {P}itoa, {N}orth- {C}ameroon where {A}nopheles gambiae displays metabolic resistance and cohabits with {A}n. funestus. {R}esults: {B}ifenthrin at 50 mg/ m2 significantly reduced anophelines' entry rate (> 80%). {T}his was not observed at 5 mg/ m2. {B}oth treatments increased exophily in {A}n. gambiae, and to a lesser extent in {A}n. funestus. {W}ith bifenthrin at high dosage, over 60% reduction in blood feeding and 75 - 90% mortality rates were observed in both vectors. {D}espite presence of holes, only a single {A}n. gambiae and two {A}n. funestus females were collected inside the treated net, and all were found dead. {T}he same trends were observed with low dosage bifenthrin though in most cases, no significant difference was found with the untreated control net. {C}onclusion: {B}ifenthrin- impregnated bednets at 50 mg/ m2 were efficient in the reduction of human- vector contact in {P}itoa. {C}onsiderable personal protection was gained against {A}n. funestus and metabolic pyrethroid resistant {A}n. gambiae populations.}, keywords = {}, booktitle = {}, journal = {{M}alaria {J}ournal}, volume = {5}, numero = {}, pages = {{NIL}_1--{NIL}_6}, ISSN = {1475-2875}, year = {2006}, DOI = {10.1186/1475-2875-5-77}, URL = {https://www.documentation.ird.fr/hor/fdi:010037641}, }