@article{fdi:010037599, title = {{H}uman {A}frican trypanosomiasis : connecting parasite and host genetics}, author = {{G}arcia, {A}ndr{\'e} and {C}ourtin, {D}avid and {S}olano, {P}hilippe and {K}offi, {M}athurin and {J}amonneau, {V}incent}, editor = {}, language = {{ENG}}, abstract = {{I}n {W}est and {C}entral {A}frica, the protozoan parasite {T}rypanosoma brucei ({T}. b.) gambiense causes a chronic form of {H}uman {A}frican trypanosomiasis ({HAT}) that might last several years, whereas {T}. b. rhodesiense refers to an acute form in {E}ast {A}frica that lasts weeks to months. {W}ithout treatment, both forms can cause death. {D}iagnosis relies on detecting parasites in blood, lymph or cerebrospinal fluid. {HAT} was no longer considered a public health problem in the 1960s, but it returned to alarming levels in the 1990s. {A}fter intensifying case detection and treatment, {WHO} recently declared the situation is under control. {H}owever, research based on host and trypanosome interactions should be encouraged to help develop innovative tools for {HAT} diagnosis and treatment to prevent re-emergence.}, keywords = {}, booktitle = {}, journal = {{T}rends in {P}arasitology}, volume = {22}, numero = {9}, pages = {405--409}, ISSN = {1471-4922}, year = {2006}, DOI = {10.1016/j.pt.2006.06.011}, URL = {https://www.documentation.ird.fr/hor/fdi:010037599}, }