@article{fdi:010035769,
  title = {{HIV}-1 subtypes and recombinants in the {R}epublic of {C}ongo},
  author = {{N}iama, {F}.{R}. and {T}oure {K}ane, {C}. and {V}idal, {N}icole and {O}bengui, {P}. and {B}ikandou, {B}. and {N}kodia, {M}.{Y}.{N}. and {M}ontavon, {C}{\'e}line and {D}iop {N}diaye, {H}. and {M}ombouli, {J}.{V}. and {M}okondzimobe, {E}. and {D}iallo, {A}.{G}. and {D}elaporte, {E}ric and {P}arra, {H}.{J}. and {P}eeters, {M}artine and {M}boup, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}o document the actual genetic diversity of {HIV}-1 strains in the {R}epublic of {C}ongo, 114 {HIV}-1 positives persons were sampled in 2003 and 2004 after their informed consent. {T}hey were attending the teaching hospital, the reference health center in {M}akelekele, {B}razzaville and the regional hospital centers in {P}ointe-{N}oire, {G}amboma and {O}uesso. {A} total of 104 samples were genetically characterized by direct sequencing of the p24 gag region and 80 were also subtyped in the {V}3-{V}5 env region. {T}he genetic subtype distribution of the {C}ongolese strains showed the predominance of subtype {A} (36.5% and 32.5% in gag and env, respectively) and {G} (30.8% and 21.25%), whereas subtype {D} strains represented 12.5% and 15%. {S}ubtypes {C}, {F}, {H}, {J}, {K} and the {CRF}s-01, -02, -05 -06, and also the recently characterized {CRF}18 were seen at lower rates. {F}inally, 4.8% (gag) and 6.25% (env) of the strains could not be classified. {M}oreover, a high intra-subtype diversity was observed in our study. {A}mong 70 strains which have been characterized in the two genomic regions, 14 (20%) appeared to be unique recombinants. {T}hese data show a high genetic variability in the {R}epublic of {C}ongo, where all the subtypes have been documented together with certain subsubtypes and several {CRF}s. (c) 2006 {B}.{V}. {A}ll rights reserved.},
  keywords = {{HIV} ; subtypes recombination ; evolution ; {C}ongo},
  booktitle = {},
  journal = {{I}nfection {G}enetics and {E}volution},
  volume = {6},
  numero = {5},
  pages = {337--343},
  ISSN = {1567-1348},
  year = {2006},
  DOI = {10.1016/j.meegid.2005.12.001},
  URL = {https://www.documentation.ird.fr/hor/fdi:010035769},
}