@article{fdi:010035739, title = {{P}rediction of {P}lasmodium falciparum placental infection according to the time of infection during pregnancy}, author = {{C}ottrell, {G}illes and {D}eloron, {P}hilippe and {F}ievet, {N}adine and {S}ow, {S}. and {G}aye, {O}. and {L}e {H}esran, {J}ean-{Y}ves}, editor = {}, language = {{ENG}}, abstract = {{M}alarial infection during pregnancy leads to placental infection, a known risk factor for low birth weight. {W}hether the stage of pregnancy at infection has a differential influence on these effects is not clearly known, but may be of importance for prevention strategies, including intermittent preventive treatment of pregnant women. {M}alaria infection during early (before 20 weeks), middle (20-28 weeks), or late (after 28 weeks) pregnancy was evaluated by logistic regression and receiver operating characteristics analysis in relation to placental infection in pregnant {S}enegalese women. {P}lasmodium falciparum infections during late pregnancy are strongly related to placental infection, as well as those that occur in middle pregnancy. {K}nowledge of parasitological events over the entire duration of pregnancy permits a highly accurate prediction of placental infection. {N}ot only malaria infections during late pregnancy increase the likelihood of placental infection. {T}he current policy of intermittent preventive treatment of pregnant women, which implies an initial antimalarial cure after 20 weeks of pregnancy, will not avoid early infections. {A}n earlier initiation of malaria prevention might improve its efficacy. (c) 2006 {E}lsevier {B}.{V}. {A}ll rights reserved.}, keywords = {malaria ; pregnancy ; placental infection ; prevention strategy ; {ROC} analysis}, booktitle = {}, journal = {{A}cta {T}ropica}, volume = {98}, numero = {3}, pages = {255--260}, ISSN = {0001-706{X}}, year = {2006}, DOI = {10.1016/j.actatropica.2006.05.009}, URL = {https://www.documentation.ird.fr/hor/fdi:010035739}, }