@article{fdi:010035725,
  title = {{C}himpanzee reservoirs of pandemic and nonpandemic {HIV}-1},
  author = {{K}eele, {B}. {F}. and {V}an {H}euverswyn, {F}. and {L}i, {Y}.{Y}. and {B}ailes, {E}. and {T}akehisa, {J}. and {S}antiago, {M}. {L}. and {B}ibollet {R}uche, {F}. and {C}hen, {Y}. {L}. and {W}ain, {L}. {V}. and {L}i{\'e}geois, {F}lorian and {L}oul, {S}. and {M}poudi {N}gol{\'e}, {E}. and {B}ienvenue, {Y}. and {D}elaporte, {E}ric and {B}rookfield, {J}. {F}. {Y}. and {S}harp, {P}. {M}. and {S}haw, {G}. {M}. and {P}eeters, {M}artine and {H}ahn, {B}. {H}.},
  editor = {},
  language = {{ENG}},
  abstract = {{H}uman immunodeficiency virus type 1 ({HIV}-1), the cause of human acquired immunodeficiency syndrome ( {AIDS}), is a zoonotic infection of staggering proportions and social impact. {Y}et uncertainty persists regarding its natural reservoir. {T}he virus most closely related to {HIV}-1 is a simian immunodeficiency virus ( {SIV}) thus far identified only in captive members of the chimpanzee subspecies {P}an troglodytes troglodytes. {H}ere we report the detection of {SIV}cpz antibodies and nucleic acids in fecal samples from wild-living {P}.t. troglodytes apes in southern {C}ameroon, where prevalence rates in some communities reached 29 to 35%. {B}y sequence analysis of endemic {SIV}cpz strains, we could trace the origins of pandemic ( group {M}) and nonpandemic ( group {N}) {HIV}-1 to distinct, geographically isolated chimpanzee communities. {T}hese findings establish {P}. t. troglodytes as a natural reservoir of {HIV}-1.},
  keywords = {},
  booktitle = {},
  journal = {{S}cience},
  volume = {313},
  numero = {5786},
  pages = {523--526},
  ISSN = {0036-8075},
  year = {2006},
  DOI = {10.1016/j.jep.2005.12.022},
  URL = {https://www.documentation.ird.fr/hor/fdi:010035725},
}