@article{fdi:010035661,
  title = {{P}hylogenetic analysis of the glucose-6-phosphate isomerase gene in {T}rypanosoma cruzi},
  author = {{B}routin, {H}{\'e}l{\`e}ne and {T}arrieu, {F}r{\'e}d{\'e}rique and {T}ibayrenc, {M}ichel and {O}ury, {B}runo and {B}arnab{\'e}, {C}hristian},
  editor = {},
  language = {{ENG}},
  abstract = {{T}rypanosoma cruzi, the agent of {C}hagas disease, has a basically clonal population structure with rare hybridization events. {T}he species is subdivided into six "{D}iscrete {T}yping {U}nits" called {DTU}sl {I}, {II}a-e, distributed into two major phylogenetic lineages, {T}. cru{Z}i {I} and {II} ({TC} {I} and {II}). {T}he glucose-6-phosphate isomerase ({G}pi) is a specific isoenzymic locus that presents homozygous profiles for {DTU}s {I}, {II}a-c, and typical heterozygous patterns, for {DTU}s {II}d and {II}e. {T}he gene was sequenced in 12 {T} cruzi stocks and in three stocks pertaining to related species. {T}he phylogenetic relationships observed confirm that the {DTU}s {I}, {II}a-c do constitute monophyletic groups. {N}evertheless, the phylogenetic hierarchy of the {DTU}s is not clearly resolved with the {GPI} gene. {T}he hybrid status of {DTU}s {II}d and {II}e was clearly supported. {S}equence analysis revealed that the allele 4 present in both {DTU}s {II}a and {II}c, previously considered as unique, displayed in fact two distinct sequences, specific for each {DTU}. {T}he level of recombination between alleles has been investigated. (c) 2005 {E}lsevier {I}nc. {A}ll rights reserved.},
  keywords = {{T}rypanosoma cruzi ; glucose 6 phosphate isomerase locus ; discrete typing unit ; hybrid ; intraspecific phylogeny ; recombination},
  booktitle = {},
  journal = {{E}xperimental {P}arasitology},
  volume = {113},
  numero = {1},
  pages = {1--7},
  ISSN = {0014-4894},
  year = {2006},
  DOI = {10.1016/j.exppara.2005.11.014},
  URL = {https://www.documentation.ird.fr/hor/fdi:010035661},
}